Sebert J L, Fardellone P, Maamer M, Agbomson F, Brazier M, Garabedian M
Rheumatology Department, Amiens Teaching Hospital, France.
Rev Rhum Engl Ed. 1996 Jul-Sep;63(7-8):498-501.
Laboratory tests were done 15 to 19 months after completion of a six-month clinical trial of oral supplementation with 1 g elemental calcium and 800 IU vitamin D per day in elderly institutionalized patients. Serum 25-OH-vitamin D and intact parathyroid hormone levels returned to normal during the trial, indicating efficacy of the supplementation in correcting the vitamin D deficiency and secondary hyperparathyroidism present before the trial. Data were available before, during, immediately after and 15 to 19 months after the trial in 37 patients. Recurrence of the vitamin D deficiency was observed after discontinuation of the supplementation.
在老年住院患者中进行了一项为期六个月的临床试验，试验内容为每日口服补充1克元素钙和800国际单位维生素D。在试验结束15至19个月后进行了实验室检测。在试验期间，血清25-羟基维生素D和完整甲状旁腺激素水平恢复正常，表明补充剂在纠正试验前存在的维生素D缺乏和继发性甲状旁腺功能亢进方面有效。37名患者在试验前、试验期间、试验刚结束后以及试验结束15至19个月后均有数据。在停止补充后观察到维生素D缺乏复发。
