B细胞组单克隆抗体对感染牛白血病病毒（BLV）和淋巴细胞增多奶牛的外周血单核细胞（PBM）的反应性。
Reactivity of monoclonal antibodies of the B cell panel on PBM from BLV-infected and lymphocytotic cows.
作者信息
Poli G, Turin L, Rocchi M, Ponti W
机构信息
Istituto di Microbiologia e Immunologia, Facoltà di Medicina Veterinaria, Università degli Studi di Milano, Italy.
出版信息
Vet Immunol Immunopathol. 1996 Aug;52(4):295-9. doi: 10.1016/0165-2427(96)05580-8.
The monoclonal antibodies included in the B cell panel of the Third Workshop on Ruminant Leukocyte Antigens were tested by flow cytometry for their reactivity with peripheral blood mononuclear cells (PBM) from normal, BLV (bovine leukemia virus)-infected but non-lymphocytotic and lymphocytotic cows. Three MoAbs probably detected pan-B cell antigens. They detected an increase in the B/T cell ratio in peripheral blood from lymphocytotic cattle. However, no changes were observed in the surface phenotypes of B cells from infected animals with MoAbs of the workshop panel.
在反刍动物白细胞抗原第三次研讨会上，对B细胞组中的单克隆抗体进行了流式细胞术检测，以确定其与正常牛、感染牛白血病病毒（BLV）但未出现淋巴细胞增多症的牛以及出现淋巴细胞增多症的牛的外周血单个核细胞（PBM）的反应性。三种单克隆抗体可能检测到了泛B细胞抗原。它们检测到淋巴细胞增多症牛外周血中B/T细胞比率增加。然而，使用研讨会小组的单克隆抗体检测感染动物的B细胞表面表型时未观察到变化。
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