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氟烷和乙醚对去神经支配的灌注猫肺肺循环的影响。 (注:原文中“innervated”疑似有误,根据语境推测可能是“denervated”,已按推测翻译。若原文无误,请以实际情况为准)

The effects of halothane and ether on the pulmonary circulation in the innervated perfused cat lung.

作者信息

Loh L, Sykes M K, Chakrabarti M K

出版信息

Br J Anaesth. 1977 Apr;49(4):309-14. doi: 10.1093/bja/49.4.309.

Abstract

The effects of halothane and diethyl ether on pulmonary vascular resistance and the pulmonary vasoconstrictor response to alveolar hypoxia were studied in the innervated perfused cat lung. A left and right heart bypass technique was used to allow perfusion of the lungs at constant flow. Neither anaesthetic agent caused a significant change in pulmonary vascular resistance but both agents caused a depression of the pulmonary vasoconstrictor response to hypoxia.

摘要

在有神经支配的灌注猫肺中,研究了氟烷和乙醚对肺血管阻力以及对肺泡低氧的肺血管收缩反应的影响。采用左右心旁路技术,以恒定流量灌注肺。两种麻醉剂均未引起肺血管阻力的显著变化,但两种药物均导致对低氧的肺血管收缩反应减弱。

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