兔体内氟烷、环丙烷和乙醚的最低肺泡有效浓度的测定。
Determination of MAC for halothane, cyclopropane and ether in the rabbit.
作者信息
MacKenzie J E
出版信息
Br J Anaesth. 1977 Apr;49(4):319-22. doi: 10.1093/bja/49.4.319.
PMID:889646
Abstract
Rabbits have a high rate of ventilation which makes it difficult to obtain a sample of end-tidal gas by the usual procedures. An occlusion technique was developed which provided a gas sample equivalent to an end-tidal gas sample. MAC values were determined using this sampling method. The values obtained +/- SEM were: cyclopropane 15.6 +/- 1.7%, halothane 0.63 +/- 0.06% and ether 2.7 +/- 0.2%.
摘要
兔子的通气率很高，这使得通过常规方法获取呼气末气体样本变得困难。于是开发了一种闭塞技术，该技术可提供与呼气末气体样本等效的气体样本。使用这种采样方法测定了最低肺泡有效浓度（MAC）值。获得的值±标准误为：环丙烷15.6±1.7%，氟烷0.63±0.06%，乙醚2.7±0.2%。
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