Yoshii Y, Moritake T, Suzuki K, Fujita K, Nose T, Satou M
Department of Neurological Surgery, University of Tsukuba, Ibaraki, Japan.
AJNR Am J Neuroradiol. 1996 Oct;17(9):1773-6.
A patient who had previously undergone resection of a malignant glioma followed by radiation therapy was found to have a focus of a high accumulation of thallous chloride Tl 201 on single-photon emission CT scans, suggesting recurrent tumor. Resection of this area was performed and the specimen showed radiation necrosis, including such reactive changes as reactive astrocytes and lymphocytes in the necrotic tissue. This case illustrates a diagnostic pitfall in the use of 201Tl single-photon emission CT for distinguishing radiation necrosis from recurrent tumor in patients treated for malignant glioma.
一名先前接受过恶性胶质瘤切除术并随后接受放射治疗的患者,在单光子发射计算机断层扫描中发现有一个高聚集的氯化铊Tl 201灶,提示肿瘤复发。对该区域进行了切除,标本显示为放射性坏死,包括坏死组织中的反应性星形胶质细胞和淋巴细胞等反应性改变。该病例说明了在使用201Tl单光子发射计算机断层扫描区分接受恶性胶质瘤治疗的患者的放射性坏死和肿瘤复发时存在的诊断陷阱。