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[初步刺激对兔乳头肌纤维重复放电的影响]

[Effect of preliminary stimulation on the repetitive firing of rabbit papillary muscle fibers].

作者信息

Gaĭnullin R Z, Kukushkin N I

出版信息

Biofizika. 1977 May-Jun;22(3):505-11.

PMID:889912
Abstract

It has been shown that the preliminary stimulation inhibits the initiation of repetitive firings (RF), increases the threshold current of RF and decreases membrane depolarization, induced by the action of constant current. It has been shown, that the higher the stimulation frequency, the higher the threshold current of RF and the lower the level of depolarization. It has been established that the time necessary for the restitution of the control firings of the tissue to the constant current after the action of the high-frequency stimulation does not exceed 2 minutes. It has been shown that the behavior of membrane potential under the constant current is characterized by two particularities: a) dissociation of the first response to switching on the constant current' b) a strong decay of the membrane potential to the resting potential.

摘要

已经表明,初步刺激会抑制重复放电(RF)的起始,增加RF的阈值电流,并降低由恒定电流作用引起的膜去极化。已经表明,刺激频率越高,RF的阈值电流越高,去极化水平越低。已经确定,在高频刺激作用后,组织恢复对恒定电流的对照放电所需的时间不超过2分钟。已经表明,在恒定电流下膜电位的行为具有两个特点:a)对接通恒定电流的第一个反应的解离;b)膜电位向静息电位的强烈衰减。

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