Eboué-Bonis D, Clauser H
Biochimie. 1977;59(5-6):527-33. doi: 10.1016/s0300-9084(77)80058-8.
The combined effects of insulin and phlorizin have been analyzed on two parameters of insulin stimulation in the surviving rat diaphragm : transport and metabolism of sugars, turnover of the phosphate groups of mononucleotides. Phlorizin (c mM) inhibits glucose transport both in the presence and absence of insulin and displays a small additional inhibitory effect on glycogen biosynthesis; with the non metabolizable glucose anlogue 3-O-methyl-D-glucose transport inhibition is demonstrated solely in the presence of insulin. No correlation is demonstrated between the rates of sugar transport, which are strongly phlorizin-sensitive, and the rates of nucleotide turnover, which show no such sensitivity.
糖的转运和代谢、单核苷酸磷酸基团的周转。根皮苷（c mM）在有和没有胰岛素的情况下均抑制葡萄糖转运，并对糖原生物合成显示出小的额外抑制作用；对于不可代谢的葡萄糖类似物3-O-甲基-D-葡萄糖，仅在有胰岛素的情况下才显示出转运抑制作用。对根皮苷敏感的糖转运速率与不显示这种敏感性的核苷酸周转速率之间未显示出相关性。
