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Structural implications in the function of L-type voltage-dependent calcium channels.

作者信息

Krizanova O

机构信息

Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovakia.

出版信息

Gen Physiol Biophys. 1996 Apr;15(2):79-87.

PMID:8899414
Abstract

The calcium channels play a key role in controlling many physiological processes in the body. Voltage dependent calcium channels have been extensively characterized in terms of their electrophysiological and pharmacological properties. The L-type voltage-dependent calcium channel is composed of several subunits, from which the alpha 1 subunit is the most important. Recent interest has been focused more on the functional implication of the subunit structures and/or their parts. Therefore, this review will concentrate on the structure-functional studies of the voltage-dependent calcium channel rather than on the progress in the study of their structure and tissue specificity.

摘要

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