Zaciu C, Koppenhöfer E, Maskaliunas R
Physiological Institute, University of Kiel, Germany.
Gen Physiol Biophys. 1996 Apr;15(2):89-107.
A mathematical formalism was developed comprising four performance parameters to analyse electronic feedback systems for voltage clamp measurements in myelinated nerve fibres. The effects of the so-called Schmidt-Lanterman incisures and of the nodal series resistance were of particular interest here. Starting from passive standard data from myelinated nerve fibres, we calculated the frequency dependence of the above mentioned parameters for the measuring systems according to Nonner, to Dodge and Frankenhaeuser, and to Bohuslavizki and coworkers. It turned out that the latter system is clearly preferable to the two remaining systems for ionic current measurements in Ranvier nodes.
开发了一种数学形式体系，它包含四个性能参数，用于分析有髓神经纤维电压钳测量中的电子反馈系统。这里特别关注所谓的施密特-兰特曼切迹和节点串联电阻的影响。从有髓神经纤维的被动标准数据出发，我们根据诺纳、道奇和弗兰肯豪泽以及博胡斯拉维茨基及其同事的方法，计算了测量系统上述参数的频率依赖性。结果表明，对于郎飞结处的离子电流测量，后一种系统明显优于其余两种系统。
