Ermolaeva L P
Biokhimiia. 1977 Jun;42(6):1006-9.
The activity of pyruvate dehydrogenase (EC 1.2.4.1) in chicken liver embryos remains constant up to the stage of hatching, and is increased by 50-70% during the first days of postnatal development and 6-7-fold on the ninth day. The enzyme activity in adult chickens is approximately equal to that in embryonic liver. The system of pyruvate dehydrogenase activation is labile; however, it may be stabilized by an addition of serum to embryonic liver homogenates. The amount of the inactive form of pyruvate dehydrogenase in embryonic liver makes up to approximately 50% of total activity. No stabilizing effect of the serum on the pyruvate dehydrogenase from young and adult chicken liver was observed.
鸡肝胚胎中丙酮酸脱氢酶（EC 1.2.4.1）的活性在孵化阶段之前保持恒定，在出生后发育的头几天增加50 - 70%，在第九天增加6 - 7倍。成年鸡的酶活性与胚胎肝脏中的大致相等。丙酮酸脱氢酶激活系统不稳定；然而，向胚胎肝脏匀浆中添加血清可使其稳定。胚胎肝脏中丙酮酸脱氢酶无活性形式的量约占总活性的50%。未观察到血清对幼鸡和成年鸡肝脏中丙酮酸脱氢酶有稳定作用。
