Ermolaeva L P
Biokhimiia. 1981 Feb;46(2):230-3.
The value of the r coefficient for pyruvate kinase (rate at 1.5 mM of phosphoenolpyruvate per rate at 0.4 mM of phosphoenolpyruvate), i.e. ratio between the enzyme forms possessing the Michaelis-Menten and cooperative kinetics, in chicken liver during ontogenesis was found to be different. The embryonic liver contains predominantly the form with the cooperative kinetics, while in the livers of 1- and 10-day-old chickens the content of the other form is increased. In the livers of adult chicken the correlation between the two forms is that typical for 10-day-old chicken.
丙酮酸激酶的r系数值（1.5 mM磷酸烯醇丙酮酸时的速率与0.4 mM磷酸烯醇丙酮酸时的速率之比），即具有米氏动力学和协同动力学的酶形式之间的比率，发现在鸡胚发育过程中鸡肝脏中的该值有所不同。胚胎肝脏中主要含有具有协同动力学的形式，而在1日龄和10日龄鸡的肝脏中，另一种形式的含量增加。在成年鸡的肝脏中，这两种形式之间的相关性与10日龄鸡的典型情况相同。
