Melendez H V, Dhawan A, Mieli-Vergani G, Rela M, Heaton N D, Pritchard J, Mowat A
Liver Transplant Surgical Service and Department of Child Health, King's College Hospital, London, United Kingdom.
Transplantation. 1996 Oct 27;62(8):1167-71. doi: 10.1097/00007890-199610270-00023.
Langerhans' cell histiocytosis (LCH) is a rare disorder of unknown etiology and pathogenesis. End-stage chronic liver disease is one presentation and orthotopic liver transplantation (OLT) has been reported in 17 cases, with variable resolution of LCH lesions postoperatively. We report a case of multisystem LCH with end-stage liver disease treated by OLT and review the overall results of OLT for children with LCH.