Lerro P, Malorgio E, Oderda G, Perugini L, Dall'Aglio M, Balocco N A
Cattedra di Pediatria, Università degli Studi, Torino.
Minerva Pediatr. 1995 Dec;47(12):541-3.
von Willebrand type I disease is an hereditary coagulation disorder characterized by a deficiency of the factor VIII complex: VIII: C, vWF:Ag, vWF:RCoF. The clinical features of this disease are spontaneous bleeding and mucosal or cutaneous bleeding following minimal injuries. The authors describe a case of a 4-year girl with recurrent episodes of gastrointestinal bleeding due to von Willebrand disease.
I型血管性血友病是一种遗传性凝血障碍疾病,其特征是VIII因子复合物缺乏,即VIII:C、血管性血友病因子抗原(vWF:Ag)、血管性血友病因子瑞斯托霉素辅因子(vWF:RCoF)。该疾病的临床特征为自发性出血以及轻微损伤后出现黏膜或皮肤出血。作者描述了一例4岁女童因血管性血友病反复发作胃肠道出血的病例。