Kono Y, Chi Q, Tomita G, Yamamoto T
Department of Ophthalmology, Gifu University School of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1996 Mar;100(3):223-9.
We compared the relationship between the neuroretinal rim area and the neural capacity (NC) index of high-pass resolution perimetry (HRP) and the differential light sensitivity (DLS) of a Humphrey Field Analyzer (HFA). Subjects were 40 eyes of 27 normal-tension glaucoma (NTG) patients. The total rim area and the area of its temporal, superior, nasal, and inferior quadrants were determined with a confocal laser tomographic scanner. Mean local NC (MLNC) was calculated using the resolution thresholds corresponding to the quadrant. Mean local DLS (MLDLS) was calculated using the data of program 30-2 of HFA. In a total of 40 eyes, NC and mean deviation were significantly correlated with the total rim area (rs = 0.422, p < 0.01: rs = 0.360, p < 0.05, respectively). NC was also significantly correlated with the total rim area in 19 eyes with early visual field changes, but not in 21 eyes with advanced changes. MLNC was significantly correlated with the superior and inferior rim areas, and MLDLS was significantly correlated with the inferior rim area. These results indicate that indices of HRP may relate to glaucomatous optic disc changes better than those of HFA in NTG, especially in patients with early visual field defects.
我们比较了高通分辨率视野计（HRP）的神经视网膜边缘面积与神经容量（NC）指数以及 Humphrey 视野分析仪（HFA）的微分光敏感度（DLS）之间的关系。研究对象为 27 例正常眼压性青光眼（NTG）患者的 40 只眼睛。使用共焦激光断层扫描仪确定总边缘面积及其颞侧、上方、鼻侧和下方象限的面积。使用对应象限的分辨率阈值计算平均局部 NC（MLNC）。使用 HFA 程序 30 - 2 的数据计算平均局部 DLS（MLDLS）。在总共 40 只眼中，NC 和平均偏差与总边缘面积显著相关（rs = 0.422，p < 0.01；rs = 0.360，p < 0.05）。在 19 只早期视野改变的眼中，NC 也与总边缘面积显著相关，但在 21 只晚期改变的眼中则不然。MLNC 与上方和下方边缘面积显著相关，MLDLS 与下方边缘面积显著相关。这些结果表明，在 NTG 中，尤其是在早期视野缺损的患者中，HRP 指标可能比 HFA 指标与青光眼性视盘改变的相关性更好。
