Weisselberg B, Dayal Y, Thompson J F, Doyle M S, Senior B, Grand R J
Department of Pediatric Gastroenterology, New England Medical Center Hospital, Boston, MA 02111, USA.
Clin Pediatr (Phila). 1996 Oct;35(10):491-5. doi: 10.1177/000992289603501002.
Ten infants with colitis due to milk protein allergy, presenting as hematochezia, whose symptoms did not resolve with the use of hydrolyzed cow-milk-based formulas, were treated with a modular lamb-meat-based formula (LOP). The patients were followed up for 3 months to 5 years. Prompt resolution of symptoms was achieved. In three patients, increased levels of creatinine and blood urea nitrogen and mild metabolic acidosis were noted, all returning to normal after the protein intake was lowered. All patients had normal growth. Seven patients were able to tolerate cow milk protein or soy at age 9-15 months. The LOP formula is well tolerated and is a safe alternative formula for infants allergic to cow milk hydrolysate formula.
10名因牛奶蛋白过敏导致结肠炎的婴儿,表现为便血,使用水解牛奶配方奶粉后症状未缓解,接受了基于羊肉的模块化配方奶粉(LOP)治疗。对这些患者进行了3个月至5年的随访。症状迅速得到缓解。3名患者出现肌酐和血尿素氮水平升高以及轻度代谢性酸中毒,在降低蛋白质摄入量后均恢复正常。所有患者生长正常。7名患者在9至15个月大时能够耐受牛奶蛋白或大豆。LOP配方奶粉耐受性良好,是对牛奶水解配方奶粉过敏婴儿的一种安全替代配方奶粉。