Sippel A E, Saueressig H, Huber M C, Hoefer H C, Stief A, Borgmeyer U, Bonifer C
Institut für Biologie III, Albert-Ludwigs-Universität Freiburg, Germany.
Methods Enzymol. 1996;274:233-46. doi: 10.1016/s0076-6879(96)74020-x.
DNase I hypersensitive sites in chromatin of eukaryotic cells mark the positions of multifactorial cis-acting elements. Mapping DH sites by indirect end labeling is a convenient procedure used for identifying regulatory elements within extensive regions of chromatin and for gaining information about their functional specificity as well as their fine structure.
