Identification of cis-acting elements as DNase I hypersensitive sites in lysozyme gene chromatin.
作者信息
Sippel A E, Saueressig H, Huber M C, Hoefer H C, Stief A, Borgmeyer U, Bonifer C
机构信息
Institut für Biologie III, Albert-Ludwigs-Universität Freiburg, Germany.
出版信息
Methods Enzymol. 1996;274:233-46. doi: 10.1016/s0076-6879(96)74020-x.
PMID:8902808
Abstract
DNase I hypersensitive sites in chromatin of eukaryotic cells mark the positions of multifactorial cis-acting elements. Mapping DH sites by indirect end labeling is a convenient procedure used for identifying regulatory elements within extensive regions of chromatin and for gaining information about their functional specificity as well as their fine structure.
摘要
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