Smith C D, Ryan S J, Hoover S L, Baumann R J
Department of Neurology, University of Kentucky Medical Center, Lexington 40536, USA.
J Neuroimaging. 1996 Oct;6(4):214-21. doi: 10.1111/jon199664214.
Aicardi's syndrome consists of multiple anomalies of the eye, brain, and axial skeleton in females, and is associated with early-onset infantile spasms and severe developmental delay. For the present study, magnetic resonance images of 20 patients with Aicardi's syndrome were obtained and the neuroimaging findings catalogued. These were compared to previously reported results and the findings correlated with current theories of fetal brain development. The results revealed a high frequency of cortical migration defects (94%) and a wide variability in the callosal defect, migrational abnormalities, and other findings in Aicardi's syndrome.
艾卡迪综合征表现为女性患者眼睛、大脑和中轴骨骼的多种异常，并伴有早发性婴儿痉挛症和严重发育迟缓。在本研究中，获取了20例艾卡迪综合征患者的磁共振图像，并对神经影像学结果进行了编目。将这些结果与先前报道的结果进行比较，并将这些发现与当前胎儿脑发育理论相关联。结果显示，艾卡迪综合征患者皮质迁移缺陷的发生率很高（94%），胼胝体缺陷、迁移异常及其他表现存在很大差异。
