严重生长激素缺乏症的患病率。
Prevalence of severe growth hormone deficiency.
作者信息
Vimpani G V, Vimpani A F, Lidgard G P, Cameron E H, Farquhar J W
出版信息
Br Med J. 1977 Aug 13;2(6084):427-30. doi: 10.1136/bmj.2.6084.427.
Abstract
Four hundred and forty-nine short children, who were all over 2-5 standard deviations below the mean height for age, were identified by screening the heights of 48 221 6- to 9-year-old children in three Scottish cities. Most were screened for growth hormone deficiency (GHD). The prevalence of severe GHD in this sample may have been as high as 1 in 4018, much higher than reported. The findings suggest that present referral patterns may account for the delayed or missed diagnosis of the condition in girls or children with less severe short stature.
摘要
通过对苏格兰三个城市48221名6至9岁儿童的身高进行筛查，确定了449名身材矮小的儿童，他们的身高比同龄人平均身高低2至5个标准差。大多数儿童接受了生长激素缺乏症（GHD）的筛查。该样本中严重生长激素缺乏症的患病率可能高达4018分之一，远高于此前报道。研究结果表明，目前的转诊模式可能导致女孩或身材矮小程度较轻的儿童病情诊断延迟或漏诊。
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