实体瘤中的异质性、生物多样性和生物反常性。

Heterogeneity, biodiversity and bioperversity in solid neoplasms.

作者信息

Rew D A

机构信息

University Surgical Unit, Glenfield Hospital, Leicester, UK.

出版信息

Eur J Surg Oncol. 1996 Oct;22(5):469-73. doi: 10.1016/s0748-7983(96)92795-x.

DOI:10.1016/s0748-7983(96)92795-x

PMID:8903487

Abstract

Heterogeneity of biological structure and function is an impediment to the analysis and treatment of human solid tumours. Its importance is frequently underestimated in clinico-pathological research. This article reviews the many facets of heterogeneity in tumour systems, and its importance to the interpretation of tumour biology.

摘要

生物结构和功能的异质性是人类实体瘤分析和治疗的一个障碍。在临床病理研究中，其重要性常常被低估。本文综述了肿瘤系统异质性的诸多方面及其对肿瘤生物学解读的重要性。