Igawa M, Urakami S, Shiina H, Ishibe T, Matsubara A, Kadena H, Usui T
Department of Urology, Shimane Medical University, Izumo, Japan.
Urol Int. 1996;56(1):13-5. doi: 10.1159/000282800.
The efficacy of ureteroscopic evaluation of upper tract abnormalities was evaluated in 40 patients. Twenty-eight patients presented with a radiologic filling defect, 9 with a filling defect and hematuria and 3 individuals exhibited hematuria alone. Cold cup biopsies revealed transitional cell carcinoma in 7 of 9 patients with papillary tumors and in 2 of 3 with nonpapillary tumors. Four patients without ureteroscopic diagnosis of urothelial cancer were found to have invasive tumors on subsequent nephroureterectomy. Of 15 patients with upper tract urothelial cancer, 12 were treated with total nephroureterectomy. Three individuals with grade 1 neoplasms received conservative ureteroscopic ablative therapy. Ureteroscopy is effective when combined with biopsy in the diagnosis and treatment of papillary lesions, but exhibits a low sensitivity in patients with invasive lesions.
对40例患者的上尿路异常进行输尿管镜评估的疗效。28例患者有放射学充盈缺损，9例有充盈缺损和血尿，3例仅表现为血尿。冷杯活检显示，9例乳头状肿瘤患者中有7例、3例非乳头状肿瘤患者中有2例为移行细胞癌。4例输尿管镜检查未诊断为尿路上皮癌的患者在随后的肾输尿管切除术中发现有浸润性肿瘤。15例上尿路尿路上皮癌患者中，12例行根治性肾输尿管切除术。3例1级肿瘤患者接受了保守性输尿管镜消融治疗。输尿管镜检查联合活检在乳头状病变的诊断和治疗中有效，但对浸润性病变患者的敏感性较低。
