Requena A, Velasco J G, Pinilla J, Gonzalez-Gonzalez A
Department of Obstetrics and Gynaecology, La Paz Hospital, Autonoma University of Madrid, Spain.
Eur J Obstet Gynecol Reprod Biol. 1995 Dec;63(2):139-41. doi: 10.1016/0301-2115(95)02243-0.
The coexistence of leukemia and pregnancy is extremely rare. This paper describes two cases of acute promyelocytic leukemia diagnosed during the second trimester of pregnancy and the most suitable approach to the management of this situation is analyzed. Possible teratogenic effects of mono- or polychemotherapy during pregnancy, depending upon the gestational age at which chemotherapy is given, are discussed.