Yoshioka A, Nishio K, Shima M
Department of Pediatrics, Nara Medical University, Japan.
Haemostasis. 1996;26 Suppl 1:139-42. doi: 10.1159/000217256.
Thrombelastgram (TEG) is an old but automated instrument that demonstrates changes occurring during blood coagulation and fibrinolysis. TEG was evaluated to be better than activated partial thromboplastin time (APTT) as a monitor of hemostatic effects when using recombinant factor VIIa (65-80 mu g/kg) in 3 hemophilia A patients with a high titer of factor VIII inhibitors. TEG was more suitable than APTT, because r, r + k and ma values of TEG were normalized at least for 4 h after the infusion, whereas APTT was variably shortened and was not always maintained at a normal level for 4 h.
血栓弹力图（TEG）是一种虽旧但自动化的仪器，可显示血液凝固和纤维蛋白溶解过程中发生的变化。在3例高滴度因子VIII抑制剂的甲型血友病患者中，当使用重组因子VIIa（65 - 80μg/kg）时，血栓弹力图被评估为比活化部分凝血活酶时间（APTT）更适合作为止血效果的监测指标。血栓弹力图比APTT更合适，因为输注后血栓弹力图的r、r + k和ma值至少在4小时内恢复正常，而APTT则不同程度缩短，且并非总能在4小时内维持在正常水平。
