Bjartmar C
Department of Cell Biology, Faculty of Health Sciences, University of Linköping, Sweden.
Neurosci Lett. 1996 Sep 27;216(2):85-8. doi: 10.1016/0304-3940(96)12990-6.
The lengths of uncompacted and partly compacted oligodendroglial sheaths in the developing rat spinal cord (SC) ventral funiculus (ages F19 and F21) and corpus callosum (CC; ages P12 and P17) were studied by serial section electron microscopy. The average newly formed uncompacted sheath is 21 and 33 microns long in the SC (F19) and CC (P12), respectively, many being less than 10 microns. In these early series, approximately 2/3 of the analysed axon length is unensheathed. The average partly compacted sheath is 102 and 69 microns long in the SC (F21) and CC (P17), respectively. Here, about 1/3 of the examined axon length is unensheathed. These results suggest that oligodendroglial sheaths initially are very short, and that they elongate actively before and during compaction. The limited unensheathed space along these axons indicate that some early sheaths must be eliminated.
通过连续切片电子显微镜研究了发育中大鼠脊髓（SC）腹侧索（F19和F21龄）和胼胝体（CC；P12和P17龄）中未压实和部分压实的少突胶质细胞鞘的长度。在脊髓（F19）和胼胝体（P12）中，新形成的未压实鞘的平均长度分别为21微米和33微米，许多鞘长度小于10微米。在这些早期阶段，大约2/3的分析轴突长度未被包裹。在脊髓（F21）和胼胝体（P17）中，部分压实鞘的平均长度分别为102微米和69微米。此处，约1/3的检查轴突长度未被包裹。这些结果表明，少突胶质细胞鞘最初非常短，并且在压实之前和压实过程中会积极伸长。沿着这些轴突有限的未包裹空间表明一些早期的鞘必须被消除。
