Bellus S B, Stewart D, Vergo J G, Kost P P, Grace J, Barkstrom S R
Buffalo Psychiatric Center, State University of New York (SUNY) at Buffalo, USA.
Brain Inj. 1996 Nov;10(11):849-60. doi: 10.1080/026990596123954.
Brain-injured individuals often experience problems with aggression which can prevent full community reintegration. Two cases involving individuals (one 4 years, one 17 years post-injury) who had been placed in a state psychiatric hospital due to aggressive and/or self-injurious behaviours are discussed. Utilizing medication dosages and behavioural acuity indicators over a 2 year period, the authors demonstrate the efficacy of lithium carbonate in treating aggressive behaviours. Lithium, in concert with other medications, not only led to a decrease in the frequency of aggressive outbursts and in the need for restrictive and costly behaviour control techniques, but also allowed for a significant reduction in the use of neuroleptic medication in one case. The authors conclude that the use of lithium, within the context of an intensive, behavioural rehabilitation programme, may yield positive effects in the control of aggressive behaviour even in long-term post-injury cases.
脑损伤患者常常会出现攻击性行为问题，这可能会阻碍他们完全重新融入社区。本文讨论了两起病例，涉及两名因攻击性行为和/或自伤行为而被送入州立精神病医院的患者（一名受伤4年，另一名受伤17年）。作者利用两年期间的药物剂量和行为敏锐度指标，证明了碳酸锂在治疗攻击性行为方面的有效性。锂与其他药物联合使用，不仅减少了攻击性行为爆发的频率，减少了对限制性和昂贵的行为控制技术的需求，而且在一个病例中还大幅减少了抗精神病药物的使用。作者得出结论，在强化行为康复计划的背景下使用锂，即使在长期受伤的病例中，也可能对控制攻击性行为产生积极效果。
