Kuroda S, Houkin K, Abe H, Tamura M
Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo.
Neurol Med Chir (Tokyo). 1996 Feb;36(2):78-86. doi: 10.2176/nmc.36.78.
The cerebral oxygenation state of five patients was continuously and non-invasively monitored using near-infrared spectroscopy (NIRS) during carotid artery balloon occlusion for comparison with somatosensory evoked potential (SEP) monitoring and regional cerebral blood flow (rCBF) measurements. In patients with marked reduction of rCBF and deteriorated SEP, NIRS demonstrated a continuous decrease in oxy-hemoglobin and total hemoglobin and an increase in deoxy-hemoglobin, indicating the occurrence of severe hypoxia in the ipsilateral hemisphere because of inadequate collateral circulation. In contrast, NIRS showed only a transient (<2 min) change in these parameters in the patients who showed no remarkable changes in SEP or rCBF, suggesting that well-developed collateral circulation immediately improved cerebral hemodynamics in the ipsilateral hemisphere. These results suggest that NIRS can provide direct and valuable information on cerebral hemodynamic changes during carotid artery balloon occlusion.
在颈动脉球囊闭塞期间，使用近红外光谱法（NIRS）对5例患者的脑氧合状态进行了连续无创监测，以与体感诱发电位（SEP）监测和局部脑血流量（rCBF）测量结果进行比较。在rCBF显著降低且SEP恶化的患者中，NIRS显示氧合血红蛋白和总血红蛋白持续下降，脱氧血红蛋白增加，表明由于侧支循环不足，同侧半球出现了严重缺氧。相比之下，在SEP或rCBF无明显变化的患者中，NIRS显示这些参数仅出现短暂（<2分钟）变化，这表明发达的侧支循环立即改善了同侧半球的脑血流动力学。这些结果表明，NIRS可以提供有关颈动脉球囊闭塞期间脑血流动力学变化的直接且有价值的信息。
