Zabarovsky E R, Kashuba V I, Gizatullin R Z, Winberg G, Zabarovska V I, Erlandsson R, Domninsky D A, Bannikov V M, Pokrovskaya E, Kholodnyuk I, Petrov N, Zakharyev V M, Kisselev L L, Klein G
Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden.
Cancer Detect Prev. 1996;20(1):1-10.
Long-range restriction site maps are of central importance for mapping the human genome. The use of clones from linking and jumping libraries for genome mapping offers a promising alternative to the laborious procedures used up until now. In the present review, this research field is analyzed with particular emphasis on the implementation of a shot-gun sequencing strategy for genome mapping and the use of NotI linking clones for analysis of rearrangements in tumors and tumor cell lines.
