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[寻找提高免疫缺陷儿童结核病再接种效果的方法]

[The search for ways to improve the efficacy of tuberculosis revaccination in children with immunological deficiency].

作者信息

Chernushenko E F, Kadan L P, Kruglova I F, Podgainaia E A

出版信息

Probl Tuberk. 1996(1):29-32.

PMID:8907482
Abstract

Clinicoimmunological examination of children to be BCG revaccinated showed 50% of them to have immunodeficiency. Primarily T-cell and macrophagal components of immunity were compromised. The study of immune response to BCG in animals with T-cell and macrophage immunodeficiency validated feasibility of improving antituberculous vaccination efficacy by using thymalin and sodium nucleinate.

摘要

对即将接种卡介苗复种的儿童进行临床免疫学检查发现,其中50%的儿童存在免疫缺陷。主要是免疫的T细胞和巨噬细胞成分受到损害。对患有T细胞和巨噬细胞免疫缺陷的动物对卡介苗的免疫反应进行研究,证实了使用胸腺素和核酸钠提高抗结核疫苗接种效果的可行性。

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