肝素诱导的体外低密度脂蛋白沉淀（HELP）治疗后糖尿病视网膜病变患者视网膜渗出物减少。病例报告。
Reduction of retinal exudates in diabetic retinopathy after heparin-induced extracorporal LDL-precipitation (HELP). A case report.
作者信息
Janknecht P, Schumann M, Hansen L L
机构信息
Freiburg University Eyeclinic, Germany.
出版信息
Eur J Ophthalmol. 1996 Jul-Sep;6(3):340-2. doi: 10.1177/112067219600600321.
INTRODUCTION
Exudative diabetic retinopathy is difficult to treat. We describe a patient in whom we believe extracorporeal LDL-precipitation (HELP) improved visual acuity.
METHODS
HELP is a variant of extracorporeal dialysis which reduces low-density lipoprotein and fibrinogen levels.
CASE REPORT
A heavily overweight patient with massive exudative diabetic retinopathy was administered HELP. Four months after starting HELP, and after vitrectomy and panretinal photocoagulation, the massive exudation was drastically lower. Visual acuity improved from 0.03 (0.02) OD (OS) to 0.25 (0.13) OD (OS).
DISCUSSION
The role of vitrectomy and panretinal photocoagulation is discussed. HELP seems to be the most probable explanation for our patient's gain in visual acuity.
引言
渗出性糖尿病视网膜病变难以治疗。我们描述了一名患者，我们认为体外低密度脂蛋白沉淀法（HELP）改善了其视力。
方法
HELP是一种体外透析变体，可降低低密度脂蛋白和纤维蛋白原水平。
病例报告
一名患有大量渗出性糖尿病视网膜病变的严重超重患者接受了HELP治疗。开始HELP治疗四个月后，在进行玻璃体切除术和全视网膜光凝术后，大量渗出明显减少。视力从右眼（左眼）0.03（0.02）提高到右眼（左眼）0.25（0.13）。
讨论
讨论了玻璃体切除术和全视网膜光凝术的作用。HELP似乎是我们的患者视力提高的最可能解释。
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