Podoleanu D, Cotoi S
Third Medical Clinic, Institute of Medicine, Tărgu-Mureş, Romania.
Rom J Intern Med. 1996 Jan-Jun;34(1-2):49-54.
This clinical study was set-up to evaluate the antihypertensive effect of ketanserin in essential hypertension (EH) associated with asymptomatic ischemic heart disease (IHD) in twenty-seven patients. Every patient received 20-40 mg ketanserin, a selective S2 serotoninergic antagonist, twice daily, for a three-month period. The blood pressure (BP) was significantly lowered during the treatment with ketanserin, much more in female patients and elderly group.