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华氏巨球蛋白血症患者中,伴有温抗体的自身免疫性溶血性贫血并发冷凝集素介导的间歇性溶血发作。

Autoimmune hemolytic anemia with warm antibodies complicated with an intercurrent attack of hemolysis with cold agglutinins in a case of Waldenström disease.

作者信息

Gologan R, Dima I, Butoianu E, Nicoară S, Coliţă D

机构信息

Fundeni Clinical Hospital, Clinic of Hematology, Bucharest, Romania.

出版信息

Rom J Intern Med. 1996 Jan-Jun;34(1-2):149-54.

PMID:8908641
Abstract

The paper presents a case of autoimmune hemolytic anemia (AIHA) with warm IgG antibodies associated with Waldenström's disease in which in the stage of compensated hemolysis after treatment, there appeared a severe hemolytic attack induced by transitory cold agglutinins with high thermal amplitude. The case described is a novelty by the intrication of two autoantibody populations which causes autoimmune hemolysis. The difference from other similar associations is discussed.

摘要

本文报道了一例伴有温IgG抗体的自身免疫性溶血性贫血(AIHA)与华氏巨球蛋白血症相关的病例,在治疗后的溶血代偿期,出现了由高热幅度的短暂冷凝集素诱发的严重溶血发作。所描述的病例因两种自身抗体群体相互作用导致自身免疫性溶血而具有新颖性。文中讨论了与其他类似关联的差异。

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