以抗凝血酶III水平衡量左炔诺孕酮（诺普兰）避孕对凝血的影响。
The effect of levenogesterol (Norplant) contraception on coagulation as measured by antithrombin-III levels.
作者信息
Pryor J A, Cooper K R, Bass J D, Hampton H L, Rock W A, Morrison J C
机构信息
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson 39216-4505, USA.
出版信息
J Miss State Med Assoc. 1996 Oct;37(10):777-9.
PURPOSE
To determine the effect of contraception given immediately postpartum on coagulation as measured by antithrombin III.
STUDY DESIGN
In this prospective study, parturients (n = 85) self selected three means of postpartum contraception: levenorgesterol implants, oral contraceptives, or a barrier method.
RESULTS
Baseline coagulation was assessed by antithrombin-III levels in each of the 85 women within 48 hours of delivery (100.35 +/- 1.61%) and at one (109.1 +/- 1.89%) and six (105.51 +/- 1.71%) weeks postpartum. There was a rise in antithrombin-III after delivery but there were no significant differences between the groups.
CONCLUSION
The levenorgesterol implant system did not cause a decrease in antithrombin-III in normal parturients.
目的
通过抗凝血酶III测定来确定产后立即进行避孕对凝血的影响。
研究设计
在这项前瞻性研究中，产妇（n = 85）自行选择三种产后避孕方法：左炔诺孕酮植入剂、口服避孕药或屏障法。
结果
在85名女性分娩后48小时内（100.35 +/- 1.61%）、产后1周（109.1 +/- 1.89%）和6周（105.51 +/- 1.71%）时，通过抗凝血酶III水平评估基线凝血情况。分娩后抗凝血酶III有所上升，但各组之间无显著差异。
结论
左炔诺孕酮植入系统不会导致正常产妇的抗凝血酶III水平降低。
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