斯蒂克勒综合征患儿眼部表现的长期随访
Long-term follow-up of ocular findings in children with Stickler's syndrome.
作者信息
Wilson M C, McDonald-McGinn D M, Quinn G E, Markowitz G D, LaRossa D, Pacuraru A D, Zhu X, Zackai E H
机构信息
Division of Ophthalmology, Children's Hospital of Philadelphia, PA 19104-4399, USA.
出版信息
Am J Ophthalmol. 1996 Nov;122(5):727-8. doi: 10.1016/s0002-9394(14)70494-5.
PURPOSE
To document the longitudinal changes in eye status of children diagnosed with Stickler's syndrome in the first decade of life.
METHOD
All patients with cleft palate were referred for eye examination. Of these, patients with systemic findings of Stickler's syndrome were included in this report.
RESULTS
Thirty-four eyes in 17 patients met inclusion criteria, with median best-corrected recognition acuity of 20/30. The mean cycloplegic refraction at presentation was -5.00 diopters, and the mean refraction at last visit was -5.50 diopters.
CONCLUSIONS
Refractive errors, cataracts, and vitreoretinal abnormalities can be detected early in life in patients with Stickler's syndrome, and refractive error changed little during the follow-up period.
目的
记录在生命的第一个十年中被诊断为斯蒂克勒综合征的儿童眼部状况的纵向变化。
方法
所有腭裂患者均被转诊进行眼部检查。其中，具有斯蒂克勒综合征全身表现的患者纳入本报告。
结果
17例患者的34只眼符合纳入标准，最佳矫正视力中位数为20/30。初诊时平均睫状肌麻痹验光度数为-5.00屈光度，末次随访时平均验光度数为-5.50屈光度。
结论
斯蒂克勒综合征患者在生命早期即可检测到屈光不正、白内障和玻璃体视网膜异常，且随访期间屈光不正变化不大。
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