Struthers M, Wong J, Janda J M
Microbial Diseases Laboratory, California Department of Health Services, Berkeley 94704-1011, USA.
Clin Infect Dis. 1996 Oct;23(4):729-33. doi: 10.1093/clinids/23.4.729.
We reviewed laboratory, clinical, and epidemiologic data on 35 patients from whom organisms belonging to the genus Roseomonas, a pink-pigmented gram-negative coccobacillus, were isolated over a 22-year period (1972-1994). Roseomonas strains were most commonly isolated from middle-aged women with one of several underlying conditions, including cancer and diabetes. Roseomonas was most commonly isolated from the blood, in association with clinical signs of sepsis. Approximately 60% of all isolates were judged to be of possible clinical significance, either as primary or secondary pathogens; 75% of all strains were recovered in pure culture. Roseomonas gilardii was the most frequently isolated species and was significantly associated with septicemia and underlying immunocompromised conditions; the species of 29% of all Roseomonas isolates could not be unequivocally identified with presently available differential tests. Genomospecies 5, currently an unnamed taxon within the genus Roseomonas, was primarily recovered as a commensal from young adults attending a sexually transmitted diseases clinic. The findings suggest that although this genus appears to have an overall low pathogenic potential for humans, Roseomonas species-in particular, R. gilardii-may be significant pathogens in persons with underlying medical complications.
我们回顾了在22年期间（1972 - 1994年）从35例患者身上分离出的属于玫瑰单胞菌属（一种粉红色革兰氏阴性球杆菌）的微生物的实验室、临床和流行病学数据。玫瑰单胞菌菌株最常从患有包括癌症和糖尿病在内的几种基础疾病之一的中年女性中分离出来。玫瑰单胞菌最常从血液中分离出来，并伴有败血症的临床症状。所有分离株中约60%被判定可能具有临床意义，作为原发性或继发性病原体；75%的菌株是在纯培养物中分离得到的。吉氏玫瑰单胞菌是最常分离出的菌种，与败血症和潜在的免疫功能低下状况显著相关；目前可用的鉴别试验无法明确鉴定所有玫瑰单胞菌分离株中29%的菌种。基因组种5，目前是玫瑰单胞菌属内一个未命名的分类单元，主要是从一家性传播疾病诊所就诊的年轻人中作为共生菌分离得到的。研究结果表明，尽管该属对人类的总体致病潜力似乎较低，但玫瑰单胞菌属菌种——特别是吉氏玫瑰单胞菌——可能是患有基础医疗并发症的人的重要病原体。
