口服青霉胺和饮食对大鼠铅中毒的影响。
The influence of oral penicillamine and diet on lead poisoning in rats.
作者信息
Aronow R, Brege B, Chen H Y, Smith R G
出版信息
Clin Toxicol. 1977 Sep;11(2):221-35. doi: 10.3109/15563657708989835.
PMID:891113
Abstract
In spite of continued lead intake, the oral chelate d-penicillamine was effective in reducing blood lead levels of lead-poisoned weanling rats on three different low-residue diets: a standard rat diet, a low calcium diet, and the trace metal salt modified EPA diet. A significant lessening of weight gain was evident in those on the low calcium diet.
摘要
尽管持续摄入铅，但口服螯合剂青霉胺能有效降低三种不同低残留饮食（标准大鼠饮食、低钙饮食以及经痕量金属盐改良的 EPA 饮食）喂养的铅中毒断奶大鼠的血铅水平。低钙饮食组大鼠的体重增加明显减少。
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