Ghista D N, Hamid M S
Comput Programs Biomed. 1977 Sep;7(3):219-31. doi: 10.1016/0010-468x(77)90030-7.
The three-dimensional left ventricular chamber geometrical model is developed from single plane cineangiocardiogram. This left ventricular model is loaded by an internal pressure monitored by cardiac catheterization. The resulting stresses in the left ventricular model chamber's wall are determined by computerized finite element procedure. For the discretization of this left ventricular model structure, a 20-node, isoparametric finite element is employed. The analysis and formulation of the computerised procedure is presented in the paper, along with the detailed algorithms and computer programs. The procedure is applied to determine the stresses in a left ventricle at an instant, during systole. Next, a portion (represented by a finite element) of this left ventricular chamber is simulated as being infarcted by making its active-state modulus value equal to its passive-state value; the neighbouring elements are shown to relieve the "infarcted" element of stress by themselves taking on more stress.
三维左心室腔几何模型是从单平面心血管造影影片构建而成的。这个左心室模型由心导管监测到的内部压力加载。左心室模型腔壁内产生的应力通过计算机化有限元程序来确定。对于这个左心室模型结构的离散化,采用了一个20节点的等参有限元。本文介绍了计算机程序的分析与公式推导,以及详细的算法和计算机程序。该程序用于确定收缩期某一时刻左心室内的应力。接下来,通过使其主动状态模量值等于被动状态值,将这个左心室腔的一部分(由一个有限元表示)模拟为梗死;结果显示相邻单元通过自身承担更多应力来减轻“梗死”单元的应力。