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使用新型人工合成补片——保加利亚不可吸收的安波克森进行的利希滕斯坦开放式无张力腹股沟疝修补术。

The Lichtenstein open tension-free inguinal hernia repair using a new prosthetic mesh-Bulgarian irresorbable ampoxen.

作者信息

Velitchkov N G, Losanoff J E, Kjossev K T, Grigorov G I, Kirov G K, Losanoff C E

机构信息

Department of Emergency Surgery, Military Medical Academy, Sofia, Bulgaria.

出版信息

Int Surg. 1996 Apr-Jun;81(2):205-9.

PMID:8912095
Abstract

The routine use of mesh for repair of inguinal hernia has been popularized by Lichtenstein and coworkers. We adopted this technique and performed it widely using a mesh unknown in the Western world. Ampoxen [multifilamented polycaproamide, impregnated with 5-Nitro-8-Hydroxyquinolinum (Nitroxolinum, DCI), MEDICA, SA, Sandanski, Bulgaria] was discovered in 1975 and proved to be an excellent prosthetic material for replacement of attenuated or destroyed abdominal wall; furthermore, this mesh is very cheap and became widely applicable in our country. This report describes our experience with the first 846 adult inguinal hernia repairs under local anesthesia using Ampoxen. All 846 patients had excellent results, without recurrence. There were nine wound infections (1.1%), 16 testicular oedemas (1.9%), no seromata and no deaths. In no patient was the prosthetic mesh removed. There were no complications related to the use of Ampoxen; this mesh is permanent, has a great degree of fibrous tissue reaction, and wide spectrum antimicrobic activity. We advocate the Lichtenstein technique using irresorbable mesh (particularly Ampoxen) for all adult groin hernias except Types 1 and 2 (according to Nyhus' classification), and for all adult recurrent groin hernias.

摘要

利希滕斯坦及其同事使腹股沟疝修补术中常规使用补片得以普及。我们采用了这项技术,并广泛使用一种在西方世界鲜为人知的补片进行手术。安波克森(多丝聚己内酰胺,浸渍有5-硝基-8-羟基喹啉(硝羟喹啉,DCI),MEDICA,SA,保加利亚桑丹斯基)于1975年被发现,事实证明它是一种用于替代变薄或受损腹壁的优质修复材料;此外,这种补片非常便宜,在我国得到了广泛应用。本报告描述了我们使用安波克森对846例成人腹股沟疝进行局部麻醉下修补的经验。所有846例患者效果极佳,无复发情况。有9例伤口感染(1.1%),16例睾丸水肿(1.9%),无血清肿发生,无死亡病例。没有患者的修复补片被移除。未出现与使用安波克森相关的并发症;这种补片是永久性的,有很大程度的纤维组织反应,且具有广谱抗菌活性。我们提倡对除1型和2型(根据尼胡斯分类法)之外的所有成人腹股沟疝以及所有成人复发性腹股沟疝采用利希滕斯坦技术,使用不可吸收补片(尤其是安波克森)。

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Am Surg. 2002 Jun;68(6):524-8; discussion 528-9.

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Susceptibility of prosthetic biomaterials to infection.人工生物材料的感染易感性。
Surg Endosc. 2006 Jan;20(1):174-5. doi: 10.1007/s00464-005-0071-3. Epub 2005 Oct 24.
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Susceptibility of prosthetic biomaterials to infection.人工生物材料的感染易感性。
Surg Endosc. 2005 Dec;19(12):1670. doi: 10.1007/s00464-005-0103-z. Epub 2005 Sep 30.
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