昆虫体内高血糖神经激素生物合成的生理效应器。

Physiological effectors of hyperglycemic neurohormone biosynthesis in an insect.

作者信息

Sowa S M, Lu K H, Park J H, Keeley L L

机构信息

Department of Entomology, Texas A&M University, Texas Agricultural Experiment Station, College Station 77843, USA.

出版信息

Mol Cell Endocrinol. 1996 Oct 14;123(1):97-105. doi: 10.1016/0303-7207(96)03901-9.

DOI:10.1016/0303-7207(96)03901-9

PMID:8912816

Abstract

Biosynthesis of hypertrehalosemic hormone (HTH) by isolated corpora cardiaca (CC) from Blaberus discoidalis cockroaches was measured for the 3-week period following adult ecdysis using an in vitro bioassay based on the incorporation of [3H]tryptophan. Synthetic rates for both males and females were highest following the molt and declined with age. Rates of HTH secretion and levels of stored HTH followed a similar pattern. We found no neural or endocrine brain effects or photophase influence on HTH synthesis. Synthesis was unaffected by treatment with 20-hydroxyecdysone or the juvenile hormone analog methoprene. In starved insects, HTH synthesis doubled and secretion increased 66% relative to fed controls.

摘要

利用基于[3H]色氨酸掺入的体外生物测定法，对成年蜕皮后3周内的蜚蠊离体心侧体（CC）合成高海藻糖血激素（HTH）的情况进行了测定。雄性和雌性的合成率在蜕皮后最高，并随年龄增长而下降。HTH的分泌率和储存的HTH水平呈现相似的模式。我们发现神经或内分泌脑效应以及光相对HTH合成没有影响。用20-羟基蜕皮酮或保幼激素类似物烯虫酯处理对合成没有影响。与喂食的对照昆虫相比，饥饿昆虫的HTH合成增加了一倍，分泌增加了66%。