Gropp C, Lehmann F G, Havemann K
Dtsch Med Wochenschr. 1977 Jul 29;102(30):1079-82. doi: 10.1055/s-0028-1105467.
Carcinoembryonic antigen (CEA) was determined at the time of diagnosis in 90 patients with lung cancer. CEA levels were elevated in 47 (52%). High CEA levels were often associated with the presence of metastases. Serial CEA determinations in 40 patients, before and after radiotherapy and chemotherapy, revealed that patients who responded to treatment had a decreased CEA level, whereas those with progressive tumour growth had increased ones. CEA assay may, therefore, be useful in detecting metastases and in helping to assess the effect of treatment in patients with lung cancer.
在90例肺癌患者确诊时测定了癌胚抗原(CEA)。47例(52%)患者的CEA水平升高。CEA水平高常与转移灶的存在相关。对40例患者在放疗和化疗前后进行连续CEA测定,结果显示对治疗有反应的患者CEA水平下降,而肿瘤进展的患者CEA水平升高。因此,CEA检测在肺癌患者转移灶检测及评估治疗效果方面可能有用。