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[颞叶胶质瘤病例中的听觉诱发磁场]

[Auditory evoked magnetic fields in cases with temporal lobe glioma].

作者信息

Kanno A, Nakasato N, Mizoi K, Yoshimoto T

机构信息

MEG Laboratory, Kohnan Hospital, Sendai, Japan.

出版信息

No Shinkei Geka. 1996 Oct;24(10):921-5.

PMID:8914151
Abstract

Auditory evoked magnetic field (AEF) is known to be suitable to separate left and right hemispheric activities while auditory evoked potential is not. To evaluate cortical auditory function in ten patients with temporal lobe gliomas, we measured AEF for monaural tone stimuli using a helmet-shaped 66-channel MEG system. Latency of the N 100 m, the most prominent peak with a latency around 90 ms, was measured in the hemisphere contralateral to the stimulus onset. In five patients, the N 100 m latency was within our normal range (mean +/- 2 s.d.). In these five cases, tumor was located in the anterior or the inferior part of the temporal lobe. We observed significant delay of the N 100 m latency in four patients and disappearance of the N 100 m in another patient. In the later five patients, tumor extended to the superior and posterior part of the temporal lobe. AEF can be used to evaluate cortical auditory function noninvasively in cases with temporal lobe gliomas.

摘要

已知听觉诱发磁场(AEF)适合区分左右半球的活动,而听觉诱发电位则不适合。为了评估10例颞叶胶质瘤患者的皮质听觉功能,我们使用头盔形状的66通道脑磁图(MEG)系统测量了单耳纯音刺激的AEF。在刺激起始对侧的半球测量了潜伏期约为90毫秒的最突出峰值N100m的潜伏期。5例患者的N100m潜伏期在我们的正常范围内(平均值±2标准差)。在这5例病例中,肿瘤位于颞叶的前部或下部。我们观察到4例患者的N100m潜伏期明显延迟,另一例患者的N100m消失。在后面5例患者中,肿瘤扩展到颞叶的上部和后部。AEF可用于无创评估颞叶胶质瘤患者的皮质听觉功能。

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