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[含溴催眠药中毒时片剂结块的放射学证据及清除(作者译)]

[Radiological evidence and removal of tablet conglomerates in intoxication with bromide-containing hypnotics (author's transl)].

作者信息

Rackwitz R, Lani K, Kiefhaber P, Halb R, Jahrmärker H

出版信息

Dtsch Med Wochenschr. 1977 Aug 19;102(33):1181-4, 1186. doi: 10.1055/s-0028-1106723.

DOI:10.1055/s-0028-1106723
PMID:891416
Abstract

If large amounts of bromide-containing hypnotics are taken together, the tablets may conglomerate in the stomach. Because of the bromide, this is radiologically demonstrable. Conventional gastric lavage does not remove such conglomerates. In order to prevent long-term late absorption with serious complications such as hypothermia, shock-lung and renal failure, previously only gastrotomy had been an effective treatment. But using gastroscopy with lavage and aspiration, such conglomerates can be removed within one to three hours. Fifteen patients in whom this technique was used were rousable within 24 hours, significantly shortening the period of intoxication. At the same time, complications may be avoided. This is also true in instances where the tablet dosage would otherwise have been fetal.

摘要

如果同时服用大量含溴化物的安眠药,药片可能会在胃中结块。由于溴化物的存在,这在放射学上是可以显示的。传统的洗胃方法无法清除这些结块。为了防止因体温过低、休克肺和肾衰竭等严重并发症导致的长期延迟吸收,以前只有胃切开术是一种有效的治疗方法。但是,通过使用带有洗胃和抽吸功能的胃镜,可以在一到三个小时内清除这些结块。采用这种技术的15名患者在24小时内可被唤醒,显著缩短了中毒时间。同时,可以避免并发症。在药片剂量原本会致命的情况下也是如此。

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