Borenstein P, Cléau M, Hautier C, Pointis D
Encephale. 1977;3(2):93-109.
Using three distinct electrophysiological tests in unanesthetized cat preparations (hippocampal theta, " caudat spindles " and stereotyped hind limb locomotor rhythms) two psychotropic benzamide derivatives (Sulpirid and Sultoprid) were tested both through systemic administration and local intracerebral microinjections. Our conclusions are that : a) Sulpirid activates the limbic system and locomotor rhythms, while deafferenting the higher " telodiencephalic " structures ; b) Sultoprid is, in revanche, at the same time deafferenting higher structure and depressing the lower one; c ) the hypothalamus represents one of the preferential targets for action of these substances.
在未麻醉的猫实验制剂中使用三种不同的电生理测试（海马θ波、“尾状核纺锤波”和刻板的后肢运动节律），通过全身给药和局部脑内微注射对两种精神otropic苯甲酰胺衍生物（舒必利和舒托必利）进行了测试。我们的结论是：a）舒必利激活边缘系统和运动节律，同时使较高的“端脑”结构传入神经阻滞；b）相反，舒托必利同时使较高结构传入神经阻滞并抑制较低结构；c）下丘脑是这些物质作用的优先靶点之一。
