Ayala-Guerrero F, Mexicano G
Centro de Neurobiología, Universidad Nacional Autónoma de México, Ciudad Universitaria, México, D.F., México.
Bol Estud Med Biol. 1995 Jan-Dec;43(1-4):19-21.
Application of a 126 V, 3 Ampers electrical current produces brain death in dogs assessed by irreversible installation of an isoelectric electroencephalogram. Cerebral death was immediate or preceded by a paroxistic activity of short duration (25 +/- 12 Seconds; Mean +/- SD). Besides the isoelectric electroencephalogram, there were immediate respiratory arrest and cardiac fibrillations followed by heart stopping. Reflexes were absent and no response to painful stimuli was observed. An appropriate utilization of the experimental method described in this study may contribute to improve the knowledge about the pathophysiology of cerebral death in humans.
应用126伏、3安培的电流会导致狗脑死亡,通过不可逆地出现等电位脑电图来评估。脑死亡是即刻发生的,或者之前有短时间的阵发活动(25±12秒;平均值±标准差)。除了等电位脑电图外,还会即刻出现呼吸停止和心脏颤动,随后心脏停搏。反射消失,对疼痛刺激无反应。本研究中描述的实验方法的适当应用可能有助于增进对人类脑死亡病理生理学的了解。