Parekh R S, Bunchman T E
Division of Pediatric Nephrology, University of Michigan, Mott Children's Hospital, Ann Arbor 48109, USA.
Adv Ren Replace Ther. 1996 Oct;3(4):326-36. doi: 10.1016/s1073-4449(96)80013-6.
Renal replacement therapy (RRT) in the pediatric intensive care unit encompasses a wide spectrum of dialysis modalities, including peritoneal dialysis, intermittent hemodialysis, and continuous hemodialysis. The choice RRT modality depends on the clinical setting, access, availability of equipment, and experience of the staff. Advances in newer access, dialysis equipment, and improved understanding of delivered dialysis have had a positive impact on survival in children with acute renal failure. Renal replacement therapy can also be used in children with specific clinical disease processes such as inborn errors of metabolism. Currently, there is no superior mode of RRT in acute renal failure. There are limited data available on the appropriate choice of modality for the specific disease state. This area requires further prospective studies to define the role of RRT in the pediatric intensive care unit.
儿科重症监护病房中的肾脏替代治疗（RRT）涵盖了广泛的透析方式，包括腹膜透析、间歇性血液透析和连续性血液透析。RRT方式的选择取决于临床情况、血管通路、设备可用性以及工作人员的经验。新型血管通路、透析设备的进展以及对所实施透析的深入理解，对急性肾衰竭患儿的生存产生了积极影响。肾脏替代治疗也可用于患有特定临床疾病过程的儿童，如先天性代谢缺陷。目前，在急性肾衰竭中不存在优越的RRT模式。关于针对特定疾病状态选择合适方式的数据有限。该领域需要进一步的前瞻性研究来明确RRT在儿科重症监护病房中的作用。
