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组织型纤溶酶原激活剂(TPA)给药后发生的动脉粥样硬化栓塞性疾病。

Atheroembolic disease following administration of tissue plasminogen activator (TPA).

作者信息

Aggarwal K, Tjahja I E

机构信息

University of Missouri-Columbia, USA.

出版信息

Clin Cardiol. 1996 Nov;19(11):906-8. doi: 10.1002/clc.4960191114.

DOI:10.1002/clc.4960191114
PMID:8914787
Abstract

Atheroembolic disease is an uncommon condition with many interesting manifestations and has been reported following various procedures. Its occurrence following thrombolytic therapy is extremely rare, with only a few case reports in the literature. However, with a widespread application of thrombolysis in patients with acute myocardial infarction, its incidence is likely to increase and therefore this entity needs to be recognized. Early recognition of the illness may help avoid further expensive and unnecessary investigations. We report two cases of atheroembolic disease following the administration of human recombinant tissue plasminogen activator (TPA).

摘要

动脉粥样硬化栓塞性疾病是一种不常见的病症,有许多有趣的表现,并且在各种操作后均有报道。其在溶栓治疗后发生极为罕见,文献中仅有少数病例报告。然而,随着溶栓在急性心肌梗死患者中的广泛应用,其发病率可能会增加,因此需要认识这一实体。早期识别该疾病可能有助于避免进一步昂贵且不必要的检查。我们报告两例在使用重组人组织型纤溶酶原激活剂(TPA)后发生动脉粥样硬化栓塞性疾病的病例。

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