Jenkins R E, Jones S A, Black M M
St John's Institute of Dermatology, St Thomas' Hospital, London, U.K.
Br J Dermatol. 1996 Oct;135(4):595-8.
Pemphigoid gestationis and bullous pemphigoid are autoimmune diseases characterized by subepidermal blisters and antibodies against the hemidesmosomal antigens: BPAG1 and BPAG2. Clinical histological and immunological similarities between pemphigoid gestationis and bullous pemphigoid suggest that they may have common pathogenetic determinants. We report two patients who presented initially with clinico-pathological features characteristic of pemphigoid gestationis but who subsequently evolved into bullous pemphigoid.
妊娠类天疱疮和大疱性类天疱疮是自身免疫性疾病，其特征为表皮下水疱以及针对半桥粒抗原BPAG1和BPAG2的抗体。妊娠类天疱疮和大疱性类天疱疮在临床、组织学和免疫学上的相似性表明，它们可能具有共同的发病机制决定因素。我们报告了两名患者，他们最初表现出妊娠类天疱疮的临床病理特征，但随后演变成了大疱性类天疱疮。
