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骨移植愈合的生物学原理。

Biological principles of bone graft healing.

作者信息

Cypher T J, Grossman J P

机构信息

Department of Surgery, Podiatry Hospital of Pittsburgh, PA 15206, USA.

出版信息

J Foot Ankle Surg. 1996 Sep-Oct;35(5):413-7. doi: 10.1016/s1067-2516(96)80061-5.

Abstract

Bone graft healing is a sequential process involving inflammation revascularization, osteogenesis remodeling, and incorporation into the host skeleton to form a mechanically efficient structure Successful incorporation is determined by the histocompatibility between host and donor. Although there is no antigenicity toward autografts, allogeneic bone may provoke an immune response. This response can be reduced through various bone processing techniques. Overall autogeneic and allogeneic bone transfers proceed to satisfactory results.

摘要

骨移植愈合是一个连续的过程,包括炎症、血管再生、骨生成重塑,以及融入宿主骨骼以形成机械效能良好的结构。成功的融入取决于宿主与供体之间的组织相容性。虽然自体移植没有抗原性,但同种异体骨可能引发免疫反应。通过各种骨处理技术可以减少这种反应。总体而言,自体和同种异体骨移植都能取得令人满意的效果。

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