Parker R E
Eur J Pharmacol. 1977 Sep 1;45(1):69-72. doi: 10.1016/0014-2999(77)90059-0.
Although adrenaline reversal is a well known phenomenon, fewer investigations have demonstrated reversal of the vascular response to noradrenaline (NA). The present studies compared subcutaneous adipose tissue vascular responses to intra-arterial NA with those of sympathetic nerve stimulation. Both NA and electrical stimulation produced vasoconstriction in adipose tissue which was reversed to beta-adrenergically mediated vasodilation following local alpha-adrenergic block.
尽管肾上腺素逆转是一种广为人知的现象，但较少有研究证实去甲肾上腺素（NA）引起的血管反应可被逆转。本研究比较了皮下脂肪组织对动脉内注射NA和交感神经刺激的血管反应。NA和电刺激均可使脂肪组织血管收缩，在局部α-肾上腺素能阻滞之后，这种收缩转变为β-肾上腺素能介导的血管舒张。
