Leblanc E, Meyer E, Zatorre R, Tampieri D, Evans A
Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Que., Canada.
Stereotact Funct Neurosurg. 1995;65(1-4):60-4. doi: 10.1159/000098898.
We have evaluated positron emission tomography (PET) scanning during sensory stimulation or during the performance of auditory, visually based or expressive language tasks (activation PET scanning) to determine its reliability in establishing the relationships of cerebral arteriovenous malformations (AVMs) to the ambient cortex in 10 patients. Five patients with a central AVM underwent activation PET scanning combined with three-dimensional MRI during vibrotactile stimulation of the contralateral hand, and 5 patients with AVMs in or around speech areas were similarly scanned during a language task. Vibrotactile stimulation identified the post-central gyrus, establishing the relationship of the AVM to the central region. The results of language activation were specific to the modality (visual, auditory, articulate) on which the task was based. Sensory PET activation scanning is reliable in identifying the pre- and post-central gyri and useful in assessing AVMs in and around the central region. A greater understanding of results in normal controls for specific visual, auditory, and expressive language tasks is necessary before language activation PET scanning can be confidently applied to clinical cases.
我们评估了10例患者在感觉刺激期间或执行听觉、视觉或表达性语言任务期间（激活正电子发射断层扫描[PET]）的PET扫描，以确定其在建立脑动静脉畸形（AVM）与周围皮质关系方面的可靠性。5例患有中央AVM的患者在对侧手部进行振动触觉刺激时接受了激活PET扫描并联合三维磁共振成像（MRI），5例在言语区域或其周围患有AVM的患者在语言任务期间进行了类似扫描。振动触觉刺激确定了中央后回，建立了AVM与中央区域的关系。语言激活结果特定于任务所基于的模式（视觉、听觉、表达）。感觉PET激活扫描在识别中央前回和中央后回方面是可靠的，并且在评估中央区域及其周围的AVM方面是有用的。在能够自信地将语言激活PET扫描应用于临床病例之前，有必要对特定视觉、听觉和表达性语言任务的正常对照结果有更深入的了解。
