Salas J M, Romero M A, Rahmani A, Faure R, Alvarez de Cienfuegos G, Tiekink E R
Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Granada, Spain.
J Inorg Biochem. 1996 Dec;64(4):259-71. doi: 10.1016/s0162-0134(96)00054-2.
The preparation and spectroscopic characterization of a series of dmtp complexes of Zn, Cd, and Hg, where dmtp is 5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine, is reported. Crystal structure analyses of [Zn(dmtp)2Br2] and [Hg(dmtp)2Cl2] reveal distorted tetrahedral geometries about the central atoms and the dmtp ligands to coordinate via the N(3) atom exclusively. In the X-ray structure of [Hdmtp]2[CdBr4].2H2O, the [Hdmtp]+ cation is protonated at the N(3) atom, there being no significant interaction between Hdmtp and cadmium. A study of the antimicrobial activity of the complexes shows that the [Cd(dmtp)X2(OH2)] (X = Cl, Br) compounds display activity against two strains.
报道了一系列锌、镉和汞的dmtp配合物（其中dmtp为5,7-二甲基[1,2,4]三唑并[1,5-a]嘧啶）的制备及其光谱表征。[Zn(dmtp)2Br2]和[Hg(dmtp)2Cl2]的晶体结构分析表明，中心原子周围的几何构型为扭曲的四面体，且dmtp配体仅通过N(3)原子进行配位。在[Hdmtp]2[CdBr4].2H2O的X射线结构中，[Hdmtp]+阳离子在N(3)原子处质子化，Hdmtp与镉之间不存在显著相互作用。对这些配合物抗菌活性的研究表明，[Cd(dmtp)X2(OH2)]（X = Cl，Br）化合物对两种菌株具有活性。
