Two cases of intravascular papillary endothelial hyperplasia developing on the sole.

Two cases of intravascular papillary endothelial hyperplasia (IPEH) are described. Each patient was a 49-year-old Japanese woman with a tender eruption on the sole. Histologically, the lesions proved to be IPEH. One of them had the typical histological appearance of IPEH, and the other showed a venous thrombus associated with histological manifestations of organization and recanalization. Newly formed vascular channels were seen at the periphery of the thrombus. These findings favored the hypothesis that IPEH usually results from peculiar organization of a thrombus.